A 2007 study suggested a correlation between oral sex and throat cancer. It is believed that this is due to the transmission of HPV, a virus that has been implicated in the majority of cervical cancers and which has been detected in throat cancer tissue in numerous studies. The study concludes that people who had one to five oral sex partners in their lifetime had approximately a doubled risk of throat cancer compared with those who never engaged in this activity and those with more than five oral sex partners had a 250 percent increased risk.[26][27][28]
Another risk of oral sex is strain on your relationship, particularly if one of you doesn’t enjoy it or has concerns about it. One partner may have anxiety about their oral sexual performance or what their partner will think of them during oral sex. Or oral sex may make one partner feel under the other partner’s control. These are all important issues to resolve before introducing oral sex into your relationship. 
Don’t forget the rest of his body. The scrotum and testicles (balls) are particularly sensitive, and most men like them to be stimulated. Try lightly licking or touching his testicles during oral sex. He might also like them to be cradled gently in one of your hands. Some men go wild when you place your hand around the top of the scrotum and gently tug down.
It doesn’t matter how memorable your oral skills may be — if your partner is distracted or stuck in her head, she is not going to be able to enjoy herself. “Oral sex offers an interesting paradox; many women love it yet it can find it so challenging to relax into the moment. This is why so many women tense up when their partner goes down," says Dr. Emily Morse, host of the Sex With Emily podcast and author of Hot Sex: Over 200 Things You Can Try Tonight. "The best thing you can say to a woman is, ‘Relax, I’ve got all night.' " Since women can worry about whether you want to be down there and may be self-conscious about how long it takes them to get off, a quick reassurance will go a long way.
On the other hand, you don’t want to get so invested in making her feel good that you wind up pressuring her to orgasm. It’s great to want to make her orgasm, but don’t make her feel like she needs to orgasm. Many women are sensitive to feeling pressured in the bedroom, but orgasm is impossible when it feels like an expectation. Her pleasure should be important to you simply because you want her to feel good, not because you want to boost your ego.
Social stigma seems to focus on the taste of women’s genitals more than men’s. In fact, men can smell and taste just as strong as women. If you're new to fellatio, you might be worried about taste and smell. If so, suggest a sexy bath or shower together and start with a clean slate. While the artificial tastes may be no better (and can be much worse) some people like to use flavored lubricant or put on a flavored condom, which may not taste better but comes with the added benefit of making oral sex a bit safer.
Really, this happens. In a recent BMJ case report, dentists detailed how a patient who regularly performed oral sex on men developed a strange lesion on the roof of his mouth, due to “blunt trauma” during fellatio. The sucking motion associated with fellatio may have also played a role, the authors wrote, causing blood to pool and clot in this area.

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